Matt
Mazzeo

Spending days tinkering and investing in new products at the forefront of AI

Formerly GP at Coatue, MD at Lowercase Capital, Agent at CAA

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01

About

Backing founders who turn intelligence into products people use every day

Formerly GP at Coatue, MD at Lowercase Capital, Agent at CAA. Worked with the founders of Replit, Cognition, Stripe, Handshake, Opensea, Mark43, Supabase and others.

"Life is a potluck, bring something to the table."

Early Days

Formative Years

Spent mostly in LA with short stints in New Zealand, New York and Canada. Passed time online in Warez rooms, Starcraft servers, competing in chemistry and playing water polo. Harvard grad (2005).

Cut My Teeth

Creative Artists Agency

  • Started the agency's digital group
  • Signed talent like Michelle Phan, Donald Glover and others
  • Launched start-ups like Funny or Die and WhoSay
  • Learned how to spot talent early
  • Learned how to build something from scratch
Second Act

Lowercase Capital

  • Managing Director, managing a portfolio of over forty seed and series A investments
  • Worked with Stripe, Handshake, Slack, Mark43, Docker and others
  • Learned how to spot early potential in products
  • Learned how to take risks at seed and series A
Leveled Up

Coatue Management

  • General Partner, launched their Venture Fund
  • Led private consumer investing strategy
  • Backed teams like Replit, Niantic, Opensea, Supabase, Deliverr and Deel
  • Learned how to evaluate companies at scale
  • Learned how to be a better board member
Now

Present Day

Angel investing in founders building the application layer of AIβ€”where model intelligence becomes daily utility.

When I'm not working, you'll find me with my wife Jesica and our daughter Josephine.

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Projects

I learn by building

Weekend experiments and side projects exploring new tools and technologies.

Jesica Mazzeo: AI Model Edition

An experiment in creating an AI-generated version of my wife, Jesica, using advanced image generation techniques.

AI Jesica in Egypt
AI Jesica goes Greek
AI Jesica in the jungle
Walkthrough
  1. Collect 20 photos of Jes
  2. Train custom Flux.dev model on Replicate
  3. Host model on Hugging Face
  4. Use Claude Sonnet to develop app on Hugging Face
  5. Test prompts for reliable image generation
Takeaways
  1. Flux.dev beat Midjourney & Runway on character consistency by a mile.
  2. Connecting Hugging Face Spaces to Replicate API was most challenging step.
  3. The uncanny valley has been fully crossed. Jes's mom was fooled by several generated images.
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Investments

Recent Angel Investments

Backing founders applying AI to real-world use cases.

Cognition AI

Devin
AI Agent

Agentic software engineering

C

Augment

Enterprise AI

AI logistics automation

A

Factor Labs

Workflow AI

AI for business-process automation

F

Luc Levesque

Travel AI
Consumer AI

In stealth

L

Limitless

Platform

Prediction market platform

L
04

Experience

Lowercase Capital

Managing Director β€” Seed & Series A

Creative Artists Agency

Started the agency's digital group, representing early online creators and incubating digital-first companies like Funny or Die and WhoSay.

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Connect

Working on something fun?
Let's connect

"Life is a potluck, bring something to the table."
Β© 2025 Matt Mazzeo. All rights reserved.